Drucken - Print

Publikationen


2018

  • Chabannon C, Kuball J, Bondanza A, Dazzi F, Pedrazzoli P, Toubert A, Ruggeri A, Fleischhauer K, Bonini C. Hematopoietic stem cell transplantation in its 60s: A platform for cellular therapies. Sci Transl Med 2018 Apr 11;10(436). pii: eaap9630. doi: 10.1126/scitranslmed.aap9630.
  • Arrieta-Bolaños E, Crivello P, Metzing M, Meurer T, Ahci M, Rytlewski J, Vignali M, Yusko E, van Balen P, Horn PA, Falkenburg JHF, Fleischhauer K. Alloreactive T Cell Receptor Diversity against Structurally Similar or Dissimilar HLA-DP Antigens Assessed by Deep Sequencing. Front Immunol 2018 Feb 19;9:280. doi: 10.3389/fimmu.2018.00280. eCollection 2018.
  • Shaw BE, Logan BR, Spellman SR, Marsh SGE, Robinson J, Pidala J, Hurley C, Barker J, Maiers M, Dehn J, Wang H, Haagenson M, Porter D, Petersdorf EW, Woolfrey A, Horowitz MM, Verneris M, Hsu KC, Fleischhauer K, Lee SJ. Development of an Unrelated Donor Selection Score Predictive of Survival after HCT: Donor Age Matters Most. Biol Blood Marrow Transplant 2018. pii: S1083-8791(18)30084-3. doi: 10.1016/j.bbmt.2018.02.006. Epub Feb 14.

2017

  • Kordelas L, Buttkereit U, Lindemann M, Koldehoff M, Klisanin V, Horn PA, Fleischhauer K, Beelen DW. αβ-T-cell depleted donor lymphocyte infusion for leukemia relapse after allogeneic stem cell transplantation. Bone Marrow Transplant 2017. Dec;52(12):1668-1670. doi: 10.1038/bmt.2017.185. Epub 2017 Sep 4.
  • Ahci M, Stempelmann K, Buttkereit U, Crivello P, Trilling M, Heinold A, Steckel NK, Koldehoff M, Horn PA, Beelen DW, Fleischhauer K. Clinical Utility of Quantitative PCR for Chimerism and Engraftment Monitoring after Allogeneic Stem Cell Transplantation for Hematologic Malignancies. Biol Blood Marrow Transplant 2017 Oct;23(10):1658-1668. pii: S1083-8791(17)30497-4. doi: 10.1016/j.bbmt.2017.05.031. Epub Jun 8.
  • Ahci M*, Toffalori C*, Bouwmans E, Crivello P, Brambati C, Pultrone C, Stempelmann K, Bost D, Mazzi B, Beelen DW, Ciceri F, Mulder W, Fleischhauer K*, Vago L*. A new tool for rapid and reliable diagnosis of HLA loss relapses after HSCT. Blood 2017 Sep 7;130(10):1270-1273. pii: blood-2017-05-784306. doi: 10.1182/blood-2017-05-784306. Epub Jun 27. *equal contribution
  • Fleischhauer K, Shaw BE. HLA-DP in unrelated hematopoietic cell transplantation revisited: challenges and opportunities. Blood 2017 Aug 31;130(9):1089-1096. pii: blood-2017-03-742346. doi: 10.1182/blood-2017-03-742346. Epub Jun 30.
  • Lorentino F, Labopin M, Fleischhauer K, Ciceri F, Mueller CR, Ruggeri A, Shimoni A, Bornhäuser M, Bacigalupo A, Gülbas Z, Koc Y, Arcese W, Bruno B, Tischer J, Blaise D, Messina G, Beelen DW, Nagler A, Mohty M. The impact of HLA matching on outcomes of unmanipulated haploidentical HSCT is modulated by GVHD prophylaxis. Blood Adv 2017 Apr 21;1(11):669-680. doi: 10.1182/bloodadvances.2017006429. eCollection 2017 Apr 25.
  • Lindsley RC, Saber W, Mar BG, Redd R, Wang T, Haagenson MD, Grauman PV, Hu ZH, Spellman SR, Lee SJ, Verneris MR, Hsu K, Fleischhauer K, Cutler C, Antin JH, Neuberg D, Ebert BL. Prognostic Mutations in Myelodysplastic Syndrome after Stem-Cell Transplantation. N Engl J Med 2017 Feb 9;376(6):536-547. doi: 10.1056/NEJMoa1611604.
  • Sanchez-Mazas A, Nunes JM, Middleton D, Sauter J, Buhler S, McCabe A, Hofmann J, Baier DM, Schmidt AH, Nicoloso G, Andreani M, Grubic Z, Tiercy JM, Fleischhauer K. Common and well-documented HLA alleles over all of Europe and within European sub-regions: A catalogue from the European Federation for Immunogenetics. HLA 2017 Feb;89(2):104-113. doi: 10.1111/tan.12956.

2016

  • Crivello P, Heinold A, Rebmann V, Ottinger HD, Horn PA, Beelen DW, Fleischhauer K. Functional distance between recipient and donor HLA-DPB1 determines non-permissive mismatches in unrelated HCT. Blood 2016 Jul 7;128(1):120-9. doi: 10.1182/blood-2015-12-686238. Epub 2016 May 9.
  • Fleischhauer K, Beelen DW. HLA mismatching as a way of reducing relapse after alternative donor transplantation. Sem Hematol 2016 Apr 4;53(2):57-64. doi: 10.1053/j.seminhematol.2016.01.010.
  • Gassa A, Kalkavan H, Jian F, Duhan V, Khairnar V, Shaabani N, Honke N, Carpinteiro A, Botezatu L, Crivello P, Dolff S, Ferencik S, Häussinger D, Khandanpour C, Fleischhauer K, Witzke O, Wahlers T, Hardt C, Lang PA, Lang KS. High Frequencies of Anti-Host Reactive CD8+ T Cells Ignore Non-Hematopoietic Antigen after Bone Marrow Transplantation in a Murine Model. Cell Physiol Biochem 2016 Mar 24;38(4):1343-1353. doi: 10.1159/000443078.
  • Fleischhauer K. Immunogenetics of HLA-DP - a new view of permissible mismatches. N Engl J Med 2015 Aug 13;373(7):669-72. doi: 10.1056/NEJMe1505539.

2015

  • Crivello P, Zito L, Sizzano F, Zino E, Maiers M, Mulder A, Toffalori C, Naldini L, Ciceri F, Vago L, Fleischhauer K. The impact of amino acid variability on alloreactivity defines a functional distance predictive of permissive HLA-DPB1 mismatches in hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2015 Feb;21(2):233-41. doi: 10.1016/j.bbmt.2014.10.017. Epub 2014 Oct 23.
  • Crucitti L, Crocchiolo R, Toffalori C, Mazzi B, Greco R, Signori A, Sizzano F, Chiesa L, Zino E, Lupo Stanghellini MT, Assanelli A, Carrabba MG, Marktel S, Marcatti M, Bordignon C, Corti C, Bernardi M, Peccatori J, Bonini C, Fleischhauer K, Ciceri F, Vago L. Incidence, risk factors and clinical outcome of leukemia relapses with loss of the mismatched HLA after partially incompatible hematopoietic stem cell transplantation. Leukemia 2015 May;29(5):1143-52. doi: 10.1038/leu.2014.314. Epub Nov 5.

2014

  • Fleischhauer K, Fernandez-Viña MA, Wang T,  Haagenson M,  Battiwalla M,  Baxter-Lowe LA,  Ciceri F,  Dehn J Gajewski J,  Hale GA,  Heemskerk MBA,  Marino SR,  McCarthy PL,  Miklos D, Oudshoorn M, Pollack MS, Reddy V, Senitzer D, Shaw BE, Waller EK, Lee SJ, Spellman SR. Risk-associations between HLA-DPB1 T cell epitope matching and outcome of unrelated hematopoietic cell transplantation are independent from HLA-DPA1. Bone Marrow Transplant 2014 Sep;49(9):1176-83. doi: 10.1038/bmt.2014.122. Epub 2014 Jun 23.
  • Lauterbach N*, Crivello P*, Wieten L, Zito L, Groeneweg M, Voorter CE, Fleischhauer K, Tilanus MG. Allorecognition of HLA-DP by CD4+ T cells is affected by polymorphism in its alpha chain. Mol Immunol 2014 May;59(1):19-29. doi: 10.1016/j.molimm.2013.12.006. Epub 2014 Jan 22. *equal contribution