Pellegrini, M., Calzascia, T., Toe, J.G., Preston, S.P., Lin, A.E., Elford, A.R., Shahinian, A., Lang, P.A., Lang, K.S., Morre, M., Assouline, B., Lahl, K., Sparwasser, T., Tedder, T.F., Paik, J.H., Depinho, R.A., Basta, S., Ohashi, P.S. & Mak, T.W. IL-7 Engages Multiple Mechanisms to Overcome Chronic Viral Infection and Limit Organ Pathology. Cell Feb 2. [Epub ahead of print](2011).

 

Lang, P.A., Recher, M., Honke, N., Scheu, S., Borkens, S., Gailus, N., Krings, C., Meryk, A., Kulawik, A., Cervantes-Barragan, L., Van Rooijen, N., Kalinke, U., Ludewig, B., Hengartner, H., Harris, N., Haussinger, D., Ohashi, P.S., Zinkernagel, R.M. & Lang, K.S. Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice. Hepatology 52, 25-32 (2010).

 

Navarini, A.A., *Lang, K.S., Verschoor, A., Recher, M., Zinkernagel, A.S., Nizet, V., Odermatt, B., Hengartner, H. & Zinkernagel, R.M. Innate immune-induced depletion of bone marrow neutrophils aggravates systemic bacterial infections. Proc Natl Acad Sci U S A 106, 7107-7112 (2009).

 

Lang, P.A., Cervantes-Barragan, L., Verschoor, A., Navarini, A.A., Recher, M., Pellegrini, M., Flatz, L., Bergthaler, A., Honda, K., Ludewig, B., Ohashi, P.S. & Lang, K.S. Hematopoietic cell-derived interferon controls viral replication and virus-induced disease. Blood 113, 1045-1052 (2009).

 

Falk, S., Wurdak, H., Ittner, L.M., Ille, F., Sumara, G., Schmid, M.T., Draganova, K., Lang, K.S., Paratore, C., Leveen, P., Suter, U., Karlsson, S., Born, W., Ricci, R., Gotz, M. & Sommer, L. Brain area-specific effect of TGF-beta signaling on Wnt-dependent neural stem cell expansion. Cell Stem Cell 2, 472-483 (2008).

 

Johansen, P., Storni, T., Rettig, L., Qiu, Z., Der-Sarkissian, A., Smith, K.A., Manolova, V., Lang, K.S., Senti, G., Mullhaupt, B., Gerlach, T., Speck, R.F., Bot, A. & Kundig, T.M. Antigen kinetics determines immune reactivity. Proc Natl Acad Sci U S A 105, 5189-5194 (2008).

 

Lohning, M., Hegazy, A.N., Pinschewer, D.D., Busse, D., Lang, K.S., Hofer, T., Radbruch, A., Zinkernagel, R.M. & Hengartner, H. Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors. J Exp Med 205, 53-61 (2008).

 

Lang, P.A., Contaldo, C., Georgiev, P., El-Badry, A.M., Recher, M., Kurrer, M., Cervantes-Barragan, L., Ludewig, B., Calzascia, T., Bolinger, B., Merkler, D., Odermatt, B., Bader, M., Graf, R., Clavien, P.A., Hegazy, A.N., Lohning, M., Harris, N.L., Ohashi, P.S., Hengartner, H., Zinkernagel, R.M. & *Lang, K.S. Aggravation of viral hepatitis by platelet-derived serotonin. Nat Med 14, 756-761 (2008).

 

Recher, M., *Lang, K.S., Navarini, A., Hunziker, L., Lang, P.A., Fink, K., Freigang, S., Georgiev, P., Hangartner, L., Zellweger, R., Bergthaler, A., Hegazy, A.N., Eschli, B., Theocharides, A., Jeker, L.T., Merkler, D., Odermatt, B., Hersberger, M., Hengartner, H. & Zinkernagel, R.M. Extralymphatic virus sanctuaries as a consequence of potent T-cell activation. Nat Med 13, 1316-1323 (2007).

 

Cervantes-Barragan, L., Zust, R., Weber, F., Spiegel, M., Lang, K.S., Akira, S., Thiel, V. & Ludewig, B. Control of coronavirus infection through plasmacytoid dendritic-cell-derived type I interferon. Blood 109, 1131-1137 (2007).

 

*Lang, K.S., Georgiev, P., Recher, M., Navarini, A.A., Bergthaler, A., Heikenwalder, M., Harris, N.L., Junt, T., Odermatt, B., Clavien, P.A., Pircher, H., Akira, S., Hengartner, H. & Zinkernagel, R.M. Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling. J Clin Invest 116, 2456-2463 (2006).

 

Navarini, A.A., Recher, M., Lang, K.S., Georgiev, P., Meury, S., Bergthaler, A., Flatz, L., Bille, J., Landmann, R., Odermatt, B., Hengartner, H. & Zinkernagel, R.M. Increased susceptibility to bacterial superinfection as a consequence of innate antiviral responses. Proc Natl Acad Sci U S A 103, 15535-15539 (2006).

 

*Lang, K.S., Recher, M., Junt, T., Navarini, A.A., Harris, N.L., Freigang, S., Odermatt, B., Conrad, C., Ittner, L.M., Bauer, S., Luther, S.A., Uematsu, S., Akira, S., Hengartner, H. & Zinkernagel, R.M. Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease. Nat Med 11, 138-145 (2005).

 

Wurdak, H., Ittner, L.M., Lang, K.S., Leveen, P., Suter, U., Fischer, J.A., Karlsson, S., Born, W. & Sommer, L. Inactivation of TGFbeta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome. Genes Dev 19, 530-535 (2005).

 

Recher, M., *Lang, K.S., Hunziker, L., Freigang, S., Eschli, B., Harris, N.L., Navarini, A., Senn, B.M., Fink, K., Lotscher, M., Hangartner, L., Zellweger, R., Hersberger, M., Theocharides, A., Hengartner, H. & Zinkernagel, R.M. Deliberate removal of T cell help improves virus-neutralizing antibody production. Nat Immunol 5, 934-942 (2004).

 

Lang, K.S., Myssina, S., Brand, V., Sandu, C., Lang, P.A., Berchtold, S., Huber, S.M., Lang, F. & Wieder, T. Involvement of ceramide in hyperosmotic shock-induced death of erythrocytes. Cell Death Differ 11, 231-243 (2004).

 

Lang, K.S., Duranton, C., Poehlmann, H., Myssina, S., Bauer, C., Lang, F., Wieder, T. & Huber, S.M. Cation channels trigger apoptotic death of erythrocytes. Cell Death Differ 10, 249-256 (2003).

 

Lang, K.S., Caroli, C.C., Muhm, A., Wernet, D., Moris, A., Schittek, B., Knauss-Scherwitz, E., Stevanovic, S., Rammensee, H.G. & Garbe, C. HLA-A2 restricted, melanocyte-specific CD8(+) T lymphocytes detected in vitiligo patients are related to disease activity and are predominantly directed against MelanA/MART1. J Invest Dermatol 116, 891-897 (2001).