Datenschutz

2012-2016


  • Jokic M, Vlasic I, Rinneburger M, Klumper N, Spiro J, Vogel W, Offermann A, Kuempers C, Fritz C, Schmitt A, Riabinska A, Wittersheim M, Michels S, Ozretic L, Florin A, Welcker D, Akyuz MD, Nowak M, Erkel M, Wolf J, Buttner R, Schumacher B, Thomale J, Persigehl T, Maintz D, Perner S, Reinhardt HC.(2016) Ercc1 Deficiency Promotes Tumorigenesis and Increases Cisplatin Sensitivity in a TP53 Context-specific Manner. Mol Cancer Res. 2016 Aug 11. pii: molcanres.0094.2016. [Epub ahead of print]
  • Hampp S, Kiessling T, Buechle K, Mansilla SF, Thomale J, Rall M, Ahn J, Pospiech H, Gottifredi V, Wiesmüller L, (2016) DNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression. Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):E4311-9. doi: 10.1073/pnas.1605828113. Epub 2016 Jul 12.
  • Bretz AC, Gittler MP, Charles JP, Gremke N, Eckhardt I, Mernberger M, Mandic R, Thomale J, Nist A, Wanzel M, Stiewe T. (2016) ΔNp63 activates the Fanconi anemia DNA repair pathway and limits the efficacy of cisplatin treatment in squamous cell carcinoma. Nucleic Acids Res. 44:3204-18. doi: 10.1093/nar/gkw036. Epub 2016 Jan 26.
  • Krüger K, Ziegler V, Hartmann C, Henninger C, Thomale J, Schupp N, Fritz G. (2016) Lovastatin prevents cisplatin-induced activation of pro-apoptotic DNA damage response (DDR) of renal tubular epithelial cells. Toxicol Appl Pharmacol. 292:103-14. doi: 10.1016/j.taap.2015.12.023
  • Paul-Konietzko K, Thomale J, Arakawa H, Iliakis G. (2015) DNA Ligases I and III Support Nucleotide Excision Repair in DT40 Cells with Similar Efficiency. Photochem Photobiol. 91:1173-80. doi: 10.1111/php.12487
  • Krüger K, Thomale J, Stojanović N, Osmak M, Henninger C, Bormann S, Fritz G.(2015) Platinum-induced kidney damage: Unraveling the DNA damage response (DDR) of renal tubular epithelial and glomerular endothelial cells following platinum injury. Biochim Biophys Acta. 2015 Mar;1854(3):685-98. doi: 10.1016/j.bbamcr.2014.12.033.
  • Keitel U, Scheel A, Thomale J, Halpape R, Kaulfuß S, Scheel C, Dobbelstein M (2015) Bcl-xL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulation.. Oncotarget. 5:11778-91.
  • Zivanovic O, Abramian A, Kullmann M, Fuhrmann C, Coch C, Hoeller T, Ruehs H, Keyver-Paik MD, Rudlowski C, Weber S, Kiefer N, Poelcher ML, Thiesler T, Rostamzadeh B, Mallmann M, Schaefer N, Permantier M, Latten S, Kalff J, Thomale J, Jaehde U, Kuhn WC (2014). HIPEC ROC I: A phase i study of cisplatin administered as hyperthermic intraoperative intraperitoneal chemoperfusion followed by postoperative intravenous platinum-based chemotherapy in patients with platinum-sensitive recurrent epithelial ovarian cancer. Int J Cancer. Jun 4. doi: 10.1002/ijc.29011.
  • Funk F, Krüger K, Henninger C, Wätjen W, Proksch P, Thomale J, Fritz G.(2014) Spongean alkaloids protect rat kidney cells against cisplatin-induced cytotoxicity. Anticancer Drugs. 25: 917-29. doi: 10.1097
  • Friboulet L, Olaussen KA, Pignon JP, Shepherd FA, Tsao MS, Graziano S, Kratzke R, Douillard JY, Seymour L, Pirker R, Filipits M, André F, Solary E, Ponsonnailles F, Robin A, Stoclin A, Dorvault N, Commo F, Vanhecke E, Saulnier P, Thomale J, Le Teuff G, Brambilla E, Soria JC (2013) ERCC1 isoform expression and DNA repair in Non-Small Cell Lung Cancer. N Engl J Med, 68:1101-10
  • Olaussen KA, Adam J, Vanhecke E, Vielh P, Pirker R, Friboulet L, Popper H, Robin A, Commo F, Thomale J, Kayitalire L, Filipits M, Le Chevalier T, André F, Brambilla E, and Soria JC (2013) PARP1 impact on DNA repair of platinum adducts: preclinical and clinical read-outs. Lung Cancer, 80:216-22
  • Nel I, Gauler TC, Eberhardt WE, Nickel AC, Schuler M, Thomale J, Hoffmann AC (2013) Formation and repair kinetics of Pt-(GpG) DNA adducts in extracted circulating tumor cells and response to platinum treatment. Br J Cancer, 109:1223-9
  • Barr M, Gray SG, Hoffmann AC, Hilger R, Thomale J, O'Flaherty JD, Fenell DA, Richard D, O'Leary JJ, O'Byrne KJ (2013) Generation and characterization of cisplatin-resistant Non-Small Cell Lung Cancer cell lines displaying a stem-like signature. PloS One, e54193. Epub 2013 Jan 17
  • Eicher C, Dewerth A, Thomale J, Ellerkamp V, Hildenbrand S, Warmann SW, Fuchs J, Armeanu-Ebinger S (2012) Effect of sorafenib combined with cytostatic agents on hepatoblastoma cell lines and xenografts. Br J Cancer, 108:334-41
  • Ziehe M, Esteban-Fernández Hochkirch U, Thomale J, Linscheid MW (2012) On the Complexity and Dynamics of in vivo Cisplatin-DNA Adduct Formation using HPLC/ICP-MS Metallomics, 4, 1098-1104
  • S. Mowaka, M. Ziehe, D. Mohamed, U. Hochkirch, J. Thomale, M.W. Linscheid (2012) Structures of Oxaliplatin-Oligonucleotide Adducts from DNA. Journal of Mass Spectrometry, 47, 1282-1293
  • Berulava T, Ziehe M, Klein-Hitpass L, Mladenov E, Thomale J, Rüther U, Horsthemke B
    FTO levels affect RNA modification and the transcriptome.
    Eur J Hum Genet., 2012, Aug 8. [Epub ahead of print]
  • Galluzzi L, Vitale I, Senovilla L, Olaussen KA, Pinna G, Eisenberg T, Goubar A, Martins I, Michels J, Kratassiouk G, Carmona-Gutierrez D, Scoazec M, Vacchelli E, Schlemmer F, Kepp O, Shen S, Tailler M, Niso-Santano M, Morselli E, Criollo A, Adjemian S, Jemaà M, Chaba K, Pailleret C, Michaud M, Pietrocola F, Tajeddine N, Rouge TD, Araujo N, Morozova N, Robert T, Ripoche H, Commo F, Besse B, Validire P, Fouret P, Robin A, Dorvault N, Girard P, Gouy S, Pautier P, Jägemann N, Nickel AC, Marsili S, Paccard C, Servant N, Hupé P, Behrens C, Behnam-Motlagh P, Kohno K, Cremer I, Damotte D, Alifano M, Midttun O, Ueland PM, Lazar V, Dessen P, Zischka H, Chatelut E, Castedo M, Madeo F, Barillot E, Thomale J, Wistuba II, Sautès-Fridman C, Zitvogel L, Soria JC, Harel-Bellan A, Kroemer G
    Prognostic impact of vitamin B6 metabolism in lung cancer.
    Cell Rep., 2012, Jul 26. [Epub ahead of print]
  • Fenske AE, Glaesener S, Bokemeyer C, Thomale J, Dahm-Daphi J, Honecker F, Dartsch DC
    Cisplatin resistance induced in germ cell tumour cells is due to reduced susceptibility towards cell death but not to altered DNA damage induction or repair..
    Cancer Lett., 2012,324:171-178. Epub 2012 May 19                                   

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