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Publikationen von 2000 bis 2004


  • Weinmann M, Betsch A, Jendrossek V, Marini P, Goecke B, Budach W, Belka C. Influence of Hypoxia on TRAIL-induced Apoptosis in tumor cells. Int J. Radiat. Oncol. Biol. Phys. 58:, 386-396 (2004).
  • Belka C*, Jendrossek V*, Verheij M, Pruschy M, Budach W. Apoptosis modulating agents in combination with radiotherapy - current status and outlook. Int J. Radiat. Oncol. Biol. Phys. 58, 542-554 (2004).
  • Weinmann M*, Jendrossek V*, Handrick R, Güner D, Goecke B, Belka C. Molecular ordering of hypoxia-induced apoptosis: critical involvement of the mitochondrial death pathway in a FADD/caspase-8 independent manner. Oncogene, 23(21), 3757-3769 (2004).
  • Albuschat R, Löwe W, Weber M, Luger P, Jendrossek V. 4-Anilinoquinazolines with Lavendustin a subunit as inhibitors of epidermal growth factor receptor tyrosine kinases: syntheses, chemical and pharmacological properties. Europ. J. Med. Chem. 39, 1001-1011 (2004).
  • Belka, W. Budach, V. Jendrossek: Molekulare Modulation der Strahlen­wirkung. Der Onkologe 10, 55-62 (2004). (Review)
  • Gruber C, Henkel M, Budach W, Belka C, Jendrossek V. Involvement of tyrosine kinase p56/Lck in apoptosis induction by anticancer drugs. Biochem Pharmacol. 67(10), 1859-1872 (2004).
  • Handrick R, Reinhardt S, Schultheiss D, Reichart T, Schüler D, Jendrossek V, Jendrossek D. Unraveling of the function of the Rhodospirillum rubrum activator of polyhydroxybutyrate (PHB) degradation: the activator is a PHB granule bound protein (phasin) J. Bact. 186(8), 2466-2475 (2004).
  • Weinmann M, Jendrossek V, Güner D, Goecke B, Belka C. Cyclic exposure to hypoxia and reoxygenation selects for tumor cells with defects in mitochondrial apoptotic pathways. FASEB J 18, 1906-1908 (2004).
  • Kugler W, Erdlenbruch B, Otten K, Jendrossek V, Eibl H, Lakomek M. Characterization of MAP kinase pathways involved in glioblastoma response to the anti-tumor lipid erucylphosphocholine. Int J Oncol 25, 1721-1727(2004).
  • Jendrossek V, Handrick R, Belka C. Celecoxib activates a novel mitochon­drial apoptosis signaling pathway. FASEB J. 17, 1547-1549 (2003).
  • Jendrossek V, Müller I, Eibl H, Belka C. Intracellular mediators of erucyl­phosphocholine-induced apoptosis. Oncogene 22, 2621-31 (2003).
  • Jendrossek V, Handrick R: Membrane targeted anticancer drugs: potent inducers of apoptosis and putative radiosensitizers. Review. Curr Med Chem Anti-Canc Agents 3, 343-353 (2003). (Review)
  • Jendrossek V, Belka C, Bamberg M: Novel chemotherapeutic agents for the treatment of glioblastoma multiforme. Review. Expert Opin Investig Drugs 12, 1899-1924 (2003). (Review)
  • Belka C, Betsch A, Marini P, Jendrossek V, Bamberg M, Budach, W. Death inducing ligands in combination with ionizing radiation. Objective and current knowledge. Strahlenther. Oncol.179, 141-151 (2003).
  • V. Jendrossek & C. Belka: Inhibition der Signaltransduktion als therapeutisches Prinzip. Der Onkologe 9, 1088-1101 (2003). (Review)
  • Belka C, Gruber C, Jendrossek V, Wesselborg S, Budach W. The tyrosine kinase Lck is involved in regulation of mitochondrial apoptosis pathways. Oncogene, 22, 176-185 (2003).
  • Marini P, Durand E, Jendrossek V, Gruber C, Budach W, Belka C. Molecular require­ments for the combined effects of TRAIL/Apo2L and ionising radiation. Radiother Oncol. 68,189-98 (2003).
  • Grassmé H, Jendrossek V, Riehle A, von Kürthy G, Berger J, Schwarz H, Weller M, Kolesnick R, Gulbins E. Host defense against Pseudomonas aeruginosa requires ceramide-rich membrane rafts. Nature Med. 9, 322-330 (2003).
  • Jendrossek V, Fillon S, Belka C, Müller I, Puttkammer B, Lang F. Apoptotic response of Chang cells to infection with Pseudomonas aeruginosa strains PAK and PAO-I: molecular ordering of the apoptosis signaling cascade and role of type IV pili. Infect. Immun. 71, 2665-73 (2003).
  • Ullrich S, Berchthold S, Boehmer C, Fillon S, Jendrossek V, Schroeder T, Pier GB, Lang F. Pseudomonas aeruginosa activates Cl(-) channels in host epithelial cells. Pflügers Archiv. 447(1), 23-28 (2003).
  • Jendrossek V, Hammersen K, Erdlenbruch B, Kugler W, Krügener R, Eibl H, Lakomek M. Structure-activity relationship of novel alkylphosphocholine derivatives: antineoplastic action on brain tumor cell lines in vitro. Cancer Chemother. Pharmacol. 50, 71-79 (2002).
  • Fillon F, Lang F, Jendrossek V. Pseudomonas aeruginosa triggered apoptosis of human epithelial cells depends on the temperature during infection. Cell. Physiol. Biochem., 12, 207-214 (2002).
  • Grassmé H, Jendrossek V, Bock J, Riehle A, Gulbins E. Ceramide-riche membrane rafts mediate CD40 clustering. J. Immunol., 168, 298-307 (2002).
  • Erdlenbruch B, Jendrossek V, Kugler W, Eibl H, Lakomek M. Increased delivery of erucylphosphocholine to C6 gliomas by chemical opening of the blood-brain barrier using intracarotid pentylglycerol in rats. Cancer Chemother. Pharmacol., 50, 299-304 (2002).
  • Rudner J, Jendrossek V, Belka C: New insights in the role of Bcl-2 - Bcl-2 and the endoplasmic reticulum. Review. Apoptosis 7, 441-447 (2002). (Review)
  • Grassmé H, Jendrossek V, Gulbins E: Molecular mechanisms of bacteria induced apoptosis. Review. Apoptosis 6, 441-445 (2001). (Review)
  • Jendrossek V, Grassmé H, Mueller I, Lang F, Gulbins E. Pseudomonas aeruginosa-induced apoptosis involves mitochondria and stress-activated protein kinases. Infect. Immun., 69, 2675-2683 (2001).
  • Jendrossek V, Kugler W, Erdlenbruch B, Eibl H, Lang F, Lakomek M. Erucylphosphocholine-induced apoptosis in chemoresistant glioblastoma cell lines: involvement of caspase activation and mitochondrial alterations. Anticancer Res., 21, 3389-3396 (2001).
  • Jendrossek V, Kugler W, Erdlenbruch B, Eibl H, Lakomek M. Induction of differentiation and tetraploidy by long-term treatment of C6 rat glioma cells with erucylphosphocholine. Int. J. Oncol., 19, 673-680 (2001).
  • Esen M, Schreiner B, Jendrossek V, Lang F, Fassbender K, Grassmé H, Gulbins E. Mechanisms of Staphylococcus aureus induced apoptosis of human endothelial cells. Apoptosis, 6, 431-439 (2001).
  • Knüpfer M M, Knüpfer H, Jendrossek V, Van Gool S, Wolff JE, Keller E. Interferon-gamma inhibits growth and migration of A172 human glioblastoma cells. Anticancer Res., 21, 3989-94 (2001).
  • Erdlenbruch B, Jendrossek V, Eibl H, Lakomek M. Transient and controllable opening of the blood-brain barrier to cytostatic and antibiotic agents by alkylglycerols in rats. Exp. Brain Res., 135, 417-422 (2000).
  • Hauck CR, Grassmé H, Bock J, Jendrossek V, Ferlinz K, Meyer TF, Gulbins E. Acid sphingomyelinase is involved in CEACAM receptor-mediated phagocytosis of Neisseria gonorrhoeae. FEBS Lett., 478, 260-266 (2000).
  • Liese J, Kloos S, Jendrossek V, Petropoulou T, Wintergerst U, Notheis G, Gahr M, Belohradsky BH. Long-term follow-up and outcome of 39 patients with chronic granulomatous disease. J. Pediatr., 137, 687-693 (2000).


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