Publikationen


2023

 

Corbett C, Finger P, Heiß-Neumann M, Bohnert J, Eder IB, Eisele M, Friesen I, Kaasch AJ, Kehrmann J, Lang R, Roedel J, Roessler S, Schmidt A, Schneitler S, Schui D, Schuler F, Sedlacek L, Serr A, Sitaru AG, Steinmann J, Wagner D, Wichelhaus TA, Hofmann-Thiel S, Hoffmann H. Development of prevalence and incidence of non-tuberculous Mycobacteria in German laboratories from 2016 to 2020. Emerg Microbes Infect. 2023 Oct 26:2276342

 

Rohde G, Eichinger M, Gläser S, Heiß-Neumann M, Kehrmann J, Neurohr C, Obradovic M, Kröger-Kilian T, Loebel T, Taube C. Best Practices for the Management of Patients with Non-Tuberculous Mycobacterial Pulmonary Disease According to a German Nationwide Analysis of Expert Centers. Healthcare (Basel). 2023 Sep 22;11(19):2610

 

Schnitker F, Liu Y, Keitsch S, Soddemann M, Verhasselt HL, Kehrmann J, Grassmé H, Kamler M, Gulbins E, Wu Y. Reduced Sphingosine in Cystic Fibrosis Increases Susceptibility to Mycobacterium abscessus Infections. Int J Mol Sci. 2023 Sep 12;24(18):14004.

 

Kehrmann J, Koch F, Zumdick S, Höwner A, Best L, Masshöfer L, Scharfenberg S, Zeschnigk M, Becker JC, Schadendorf D, Buer J, Roesch A. Reduced Staphylococcus Abundance Characterizes the Lesional Microbiome of Actinic Keratosis Patients after Field-Directed Therapies. Microbiol Spectr. 2023 Jun 15;11(3):e0440122 

 

2022

 

Kavvalou A, Stehling F, Tschiedel E, Kehrmann J, Walkenfort B, Hasenberg M, Olivier M, Steindor M. Biofilm infection of a central venous port-catheter caused by Mycobacterium avium complex in an immunocompetent child with cystic fibrosis. BMC Infect Dis 22, 921 (2022).

 

Wetzstein N, Diricks M, Kohl TA, Wichelhaus TA, Andres S, Paulowski L, Schwarz C, Lewin A, Kehrmann J, Kahl BC, Dichtl K, Hügel C, Eickmeier O, Smaczny C, Schmidt A, Zimmermann S, Nährlich L, Hafkemeyer S, Niemann S, Maurer FP, Hogardt M. Molecular Epidemiology of Mycobacterium abscessus Isolates Recovered from German Cystic Fibrosis Patients. Microbiol Spectr. 2022 Aug 31;10(4):e0171422. doi: 10.1128/spectrum.01714-22. Epub 2022 Aug 8. PMID: 35938728; PMCID: PMC9431180.

 

Schildhaus HU, Steindor M, Kölsch B, Herold T, Buer J, Kehrmann J. GenoType CM Direct® and VisionArray Myco® for the Rapid Identification of Mycobacteria from Clinical Specimens. J Clin Med. 2022 Apr 25;11(9):2404

 

Reinold J, Farahpour F, Schoerding AK, Fehring C, Dolff S, Konik M, Korth J, van Baal L, Buer J, Witzke O, Westendorf AM, Kehrmann J. The Fungal Gut Microbiome Exhibits Reduced Diversity and Increased Relative Abundance of Ascomycota in Severe COVID-19 Illness and Distinct Interconnected Communities in SARS-CoV-2 Positive Patients. Front Cell Infect Microbiol. 2022 Apr 19;12:848650

 

Verhasselt HL, Kudla M, Herbstreit F, Weidener S, Reckinger F3, Scholtysik R, Buer J, Kehrmann J. Mycobiome Analysis Reveals High Fungal Richness in Lungs of Acute Respiratory Distress Syndrome after Septic Tank Incident. Arch Clin Med Case Rep 2022; 6 (2): 229-233

 

Wilk C, Effenberg L, Abberger H, Steenpass L, Hansen W, Zeschnigk M, Kirschning C, Buer J, Kehrmann J.: CRISPR/Cas9-mediated demethylation of FOXP3-TSDR toward Treg-characteristic programming of Jurkat T cells. Cell Immunol. 2022 Jan;371:104471.

 

2021

 

de Carvalho TS, Singh V, Yusuf AM, Wang J, Schultz Moreira AR, Sanchez-Mendoza EH, Sardari M, Nascentes Melo LM, Doeppner TR, Kehrmann J, Scholtysik R, Hitpass L, Gunzer M, Hermann DM.   Post-ischemic protein restriction induces sustained neuroprotection, neurological recovery, brain remodeling, and gut microbiota rebalancing. Brain Behav and Immun. 2021 Nov 27:S0889-1591(21)00612-7. doi: 10.1016/j.bbi.2021.11.016. Online ahead of print.

Reinold J, Farahpour F, Fehring C, Dolff S, Konik M, Korth J, van Baal L, Hoffmann D, Buer J, Witzke O, Westendorf AM and Kehrmann J. (2021) A Pro-Inflammatory Gut Microbiome Characterizes SARSCoV-2 Infected Patients and a Reduction in the Connectivity of an Anti-Inflammatory Bacterial Network Associates With Severe COVID-19. Front. Cell. Infect. Microbiol. 11:747816. doi: 10.3389/fcimb.2021.747816     

Steindor M, Stehling F, Olivier M, Kehrmann J, Diricks M, Maurer FP, Horn PA, Straßburg S, Welsner M, Sutharsan S and Lindemann M. Species-Specific Interferon-Gamma Release Assay for the Diagnosis of Mycobacterium abscessus Complex Infection. Front. Microbiol. 2021 Jul 12;12:692395.

Adamczyk A, Pastille E, Kehrmann J, Vu VP, Geffers R, Wasmer MH, Kasper S, Schuler M, Lange CM, Muggli B, Rau TT, Klein D, Hansen W, Krebs P, Buer J, Westendorf AM. GPR15 Facilitates Recruitment of Regulatory T cells to Promote Colorectal Cancer. Cancer Res. 2021 Jun 1;81(11):2970-2982.  

Chapot V, Effenberg L, Dohmen-Ruetten J, Buer J, Kehrmann J. Evaluation of the Accelerate Pheno System for Rapid Identification and Antimicrobial Susceptibility Testing of Positive Blood Culture Bottles Inoculated with Primary Sterile Specimens from Patients with Suspected Severe Infections. J Clin Microbiol. 2021 Apr 20;59(5):e02637-20.

 

2020

 

Mücke MM, Rüschenbaum S, Mayer A, Mücke VT, Schwarzkopf KM, Zeuzem S, Kehrmann J, Scholtysik R, Lange CM. Stool and sputum microbiome during quinolone prophylaxis of spontaneous bacterial peritonitis: an exploratory study. Gut Pathogens. 2020 Oct 30.  equally contributed

 

Kehrmann J, Popp W, Delgermaa B, Otgonbayar D, Gantumur T, Buer J, Tsogbadrakh N.: Two fatal cases of plague after consumption of raw marmot organs. Emerg Microbes Infect. 2020 Aug 7:1-6.

 

Madhusudhan N, Pausan MR, Halwachs B, Durdević M, Windisch M, Kehrmann J, Patra V, Wolf P, Boukamp P, Moissl-Eichinger C, Cerroni L, Becker JC, Gorkiewicz G.: Molecular Profiling of Keratinocyte Skin Tumors Links Staphylococcus aureus Overabundance and Increased Human β-Defensin-2 Expression to Growth Promotion of Squamous Cell Carcinoma. Cancers (Basel). 2020 Feb 26;12(3):541.

 

Dolff S, Kehrmann J, Eisermann P, Dalbah S, Tappe D, Rating P.: Case Report: Thelazia callipaeda Eye Infection: The First Human Case in Germany. Am J Trop Med Hyg. 2020 Feb;102(2):350-351.

 

Kehrmann J, Effenberg L, Wilk C, Schoemer D, Phuong NNT, Adamczyk A, Pastille E, Scholtysik R, Klein-Hitpass L, Klopfleisch R, Westendorf AM, Buer J.: Depletion of Foxp3+ regulatory T cells is accompanied by an increase in the relative abundance of Firmicutes in the murine gut microbiome. Immunology. 2020 Mar;159(3):344-353

 

 

2019

 

Turki AT, Bayraktar E, Basu O, Benkö T, Yi JH, Kehrmann J, Tzalavras A, Liebregts T, Beelen DW, Steckel NK.: Ileostomy for steroid-resistant acute graft-versus-host disease of the gastrointestinal tract. Ann Hematol. 2019 Oct;98(10):2407-2419.

 

Reinsch N, Streeck H, Holzendorf V, Schulze C, Neumann T, Brockmeyer NH, Kehrmann J, Schadendorf D, Esser S.: B-type natriuretic peptides for the prediction of cardiovascular events and mortality in patients living with HIV: Results from the HIV-HEART study. Int J Cardiol. 2019 Apr 15;281:127-132.

 

 

2018

 

Kehrmann J, Menzel J, Saeedghalati M, Obeid R, Schulze C, Holzendorf V, Farahpour F, Reinsch N, Klein-Hitpass L, Streeck H, Hoffmann D, Buer J, Esser S.: Gut microbiota in HIV-infected individuals linked to coronary heart disease. The Journal of Infectious Diseases. 2018 Sep 7 https://doi.org/10.1093/infdis/jiy524.

 

Ross B, Sperling A, Kehrmann J, Goer S.: Ist eine Routineuntersuchung von Bronchoskopen auf eine Belastung mit Mykobakterien notwendig? HygMed 2018; 43(9): D79-D82.

 

Kehrmann J, Chapot V, Buer J, Rating P, Bornfeld N, Steinmann J.: Diagnostic performance of blood culture bottles for vitreous culture compared to conventional microbiological cultures in patients with suspected endophthalmitis. Eur J Clin Microbiol Infect Dis. 2018 Jan 9

 

2017

 

Kehrmann J, Veckollari B, Schmidt D, Schildgen O, Schildgen V, Wagner N, Zeschnigk M, Klein-Hitpass L, Witzke O, Buer J, Steinmann J.: The lung microbiome in patients with pneumocystosis. BMC Pulm Med. 2017 Dec 4;17(1):170

 

Wöchtl B, Gunzer F, Gerner W, Gasse H, Koch M, Bagó Z, Ganter M, Weissenböck H, Dinhopl N, Coldewey SM, von Altrock A, Waldmann KH, Saalmüller A, Zimmermann K, Steinmann J, Kehrmann J, Klein-Hitpass L, Blom J, Ehricht R, Engelmann I, Hennig-Pauka I.: Comparison of clinical and immunological findings in gnotobiotic piglets infected with Escherichia coli O104:H4 outbreak strain and EHEC O157:H7. Gut Pathog. 2017 May 25;9:30

 

2016

 

Kehrmann J, Kurt N, Rueger K, Bange FC, Buer J.: GenoType NTM-DR for Identifying Mycobacterium abscessus Subspecies and Determining Molecular Resistance. J Clin Microbiol. 2016 Jun;54(6):1653-5.

 

Abel S, Ueffing K, Tatura R, Hutzler M, Hose M, Matuschewski K, Kehrmann J, Westendorf AM, Buer J, Hansen W.: Plasmodium yoelii infection of BALB/c mice results in expansion rather than induction of CD4(+) Foxp3(+) regulatory T cells. Immunology. 2016 Jun;148(2):197-205.

 

Kehrmann J, Schoerding AK, Murali R, Wessel S, Koehling HL, Mosel F, Buer J.: Performance of Vitek MS in identifying nontuberculous mycobacteria from MGIT liquid medium and Lowenstein-Jensen solid medium. Diagn Microbiol Infect Dis. 2016 Jan;84(1):43-7

 

Kehrmann J, Wessel S, Murali R, Hampel A, Bange FC, Buer J, Mosel F.: Principal component analysis of MALDI TOF MS mass spectra separates M. abscessus (sensu stricto) from M. massiliense isolates. BMC Microbiol. 2016 Mar 1;16:24.

 

2015

 

 

 

Tatura R, Zeschnigk M, Hansen W, Steinmann J, Vidigal PG, Hutzler M, Pastille E, Westendorf AM, Buer J, Kehrmann J.: Relevance of Foxp3⁺ regulatory T cells for early and late phases of murine sepsis. Immunology 2015 Sep;146(1):144-56

 

2014

 

 

 

Vidigal PG, Müsken M, Becker KA, Häussler S, Wingender J, Steinmann E, Kehrmann J, Gulbins E, Buer J, Rath PM, Steinmann J.: Effects of green tea compound epigallocatechin-3-gallate against Stenotrophomonas maltophilia infection and biofilm. PLoS One. 2014 Apr 1;9(4):e92876

 

Kehrmann J., Tatura R., Zeschnigk M., Probst-Kepper M., Geffers R., Steinmann J., Buer J.: Impact of 5-Aza-2`-deoxycytidine and Epigallocatechin-3-gallate for induction of human regulatory T cells. Immunology. 2014 Jul

 

2012

 

 

 

Tatura R., Zeschnigk M., Adamzik M., Probst-Kepper M., Buer J., Kehrmann J.: Quantification of Regulatory T Cells in Septic Patients by Real-Time PCR-Based Methylation Assay. PLoS ONE 2012; 7(11):e49962.

 

2011

 

 

Kehrmann J., Zeschnigk M., Buer J., Probst-Kepper M: FOXP3 Expression in GARP-Transduced Helper T Cells Is Not Associated with FOXP3 TSDR Demethylation, Transfus. Med. Hemother. 2011 Oct;38(5):287-291

 

Kehrmann J, Kaase M, Szabados F, Gatermann SG, Buer J, Rath PM, Steinmann J.: Vancomycin MIC creep in MRSA blood culture isolates from Germany: a regional problem? Eur J Clin Microbiol Infect Dis. 2011 May; 30(5):677-83.

Kirchhoff L, Dittmer S, Furnica DT, Buer J, Steinmann E, Rath PM, Steinmann J. Inhibition of Azole-resistant Aspergillus fumigatus Biofilm at various Formation stages by antifungal drugs, including olorofim.Journal of Antimicrobial Chemotherapy 2022, Mar 15;dkac062. doi: 10.1093/jac/dkac062. Onlin ahead of print.

Corbett C, Finger P, Heiß-Neumann M, Bohnert J, Eder IB, Eisele M, Friesen I, Kaasch AJ, Kehrmann J, Lang R, Roedel J, Roessler S, Schmidt A, Schneitler S, Schui D, Schuler F, Sedlacek L, Serr A, Sitaru AG, Steinmann J, Wagner D, Wichelhaus TA, Hofmann-Thiel S, Hoffmann H. Development of prevalence and incidence of non-tuberculous Mycobacteria in German laboratories from 2016 to 2020. Emerg Microbes Infect. 2023 Oct 26:2276342