Publications


2015 Impact Faktor
1. Denecke B, Horsch LD, Radtke S, Fischer JC, Horn PA, Giebel B. Human endothelial colony-forming cells expanded with an improved protocol are a useful endothelial cell source for scaffold-based tissue engineering.J Tissue Eng Regen Med. 2015; 9 (11): E84-97 5.2
   
2. Murke F, Castro SVC, Giebel B, Görgens A. Concise Review: Asymmetric Cell Divisions in Stem Cell Biology. Symmetry. 2015; 7: 2025-2037 0.8
   
3. Loeffek S, Ullrich N, Görgens A, Murke F, Eilebrecht M, Menne C, Giebel B, Schadendorf D, Singer BB, Helfrich I. CEACAM1-4L promotes anchorage-independent growth in melanoma. Front Oncol. 2015; 5: 234  
   
4. Görgens A, Horn PA. From Basic Biology to Engineering and Clinical Translation of Stem Cells. Cellular Reprogramming. December 2015; 17 (6): 415-418 1.8
   
5. Börger V, Görgens A, Rohde E, Giebel B. Therapeutisches Potenzial von extrazellulären Vesikeln aus mesenchymalen Stamm- bzw. Stromazellen. Transfusionsmedizin. 2015; 5: 131–137  
   
6. Doeppner TR, Herz J, Gorgens A, Schlechter J, Ludwig AK, Radtke S, de Miroschedji K, Horn PA, Giebel B and Hermann DM. Extracellular vesicles improve post-stroke neuroregeneration and prevent post-ischemic immunosuppression. Stem Cells Transl Med. 2015; 4 (10): 1131-43 5.7
   
7. Görgens A, Giebel B. Wie unser Blut entsteht – neue Erkenntnisse zur Hämatopoese. BIOspektrum. 2015; 21 (3): 290-293  
   
8. Yáñez-Mó M, Siljander PRM, Andreu Z, [...], Giebel B, [...], Vasconcelos MH, Wauben MHM, De Wever O. Biological properties of extracellular vesicles and their physiological functions. J Extracell Vesicles. 2015; 4: 27066  
   
9. Graffmann N, Brands J, Görgens A, Vitoriano da Conceição Castro S, Santourlidis S, Reckert A, Michele I, Ritz-Timme S, Fischer JC, Adjaye J, Kögler G, Giebel B, Uhrberg M. Age-related increase of EED expression in early hematopoietic progenitor cells is associated with global increase of the histone modification H3K27me3. Stem Cells Dev. 2015 May 11 [Epub] 4.2
   
10. Radtke S, Görgens A, Kordelas L, Schmidt M, Kimmig KR, Köninger A, Horn PA, Giebel B. CD133 allows elaborated discrimination and quantification of haematopoietic progenitor subsets in human haematopoietic stem cell transplants. Br. J. Haematol. 2015; 169 (6):868-78 5.0
   
11. Krawczyk A, Dirks M, Kasper M, Buch A, Dittmer U, Giebel B, Wildschütz L, Busch M, Goergens A, Schneweis KE, Eis-Hübinger AM, Sodeik B, Heiligenhaus A, Roggendorf M, Bauer D. Prevention of Herpes Simplex Virus Induced Stromal Keratitis by a Glycoprotein B-Specific Monoclonal Antibody PLoS ONE. 2015; 10(1): e0116800 3.5
   
2014  
1. Radtke, S., Giebel, B., Wagner, W., and Horn, P.A. Platelet lysates and their role in cell therapy. ISBT Science Series. 2014; 9(1): 193-7  
   
2. Brandau S, Jakob M, Bruderek K, Bootz F, Giebel B, Radtke S, Mauel K, Jäger M, Flohé SB, Lang S. Mesenchymal stem cells augment the anti-bacterial activity of neutrophil granulocytes. PLoS One. 2014; 9(11): e114201 3.5
   
3. Müller CR, Mytilineos J, Ottinger H, Arnold R, Bader P, Beelen D, Bornhäuser M, Dreger P, Eiermann T, Einsele H, Faé I, Fischer G, Füssel M, Holler E, Holzberger G, Horn PA, Kröger N, Lindemann M, Seidl C, Spriewald B, Süsal C, Blasczyk R, Finke J. Deutscher Konsensus 2013 zur immungenetischen Spenderauswahl für die allogene Stammzelltransplantation. Transfusionsmedizin. 2014; 4: 190-6  
   
4. Kim DK, Lee J, Kim SR, Choi DS, Yoon YJ, [...], Giebel B, [...], Zeidler R, Gho YS. EVpedia: A Community Web Portal for Extracellular Vesicles Research. Bioinformatics. 2014; 31 (6): 933-9 4.6
   
5. Görgens A, Ludwig AK, Möllmann M, Krawczyk A, Dürig J, Hanenberg H, Horn PA, Giebel B. Multipotent hematopoietic progenitors divide asymmetrically to create progenitors of the Lympho-Myeloid and Erythro-Myeloid Lineages. Stem Cell Reports. 2014; 3(6): 1058-72 5.4
   
6. Malyar NM, Radtke S, Malyar K, Arjumand J, Horn PA, Kröger K, Freisinger E, Reinecke H, Giebel B, Brock FE. Autologous Bone Marrow Mononuclear Cell Therapy Improves Symptoms in Patients with End-Stage Peripheral Arterial Disease and Reduces Inflammation Associated Parameters. Cytotherapy. 2014; 16(9): 1270-9 3.3
   
7. Kordelas L, Rebmann V, Ludwig AK, Radtke S, Ruesing J, Doeppner TR, Epple M, Horn PA, Beelen DW, Giebel B. MSC-derived exosomes: a novel tool to treat therapy-refractory graft-versus-host disease. Leukemia. 2014; 28(4): 970-3 10.2
   
8. Hemeda H, Giebel B, Wagner W. Evaluation of human platelet lysate versus fetal bovine serum for culture of mesenchymal stromal cells. Cytotherapy. 2014; 16(2): 170-80 3.3
   
2013  
1. Görgens A, Radtke S, Horn PA, Giebel B. New Relationships of Human Hematopoietic Lineages Facilitate Detection of Multipotent Hematopoietic Stem and Progenitor Cells. Cell Cycle. 2013; 12(22): 3478-82 5.2
   
2. Muturi HT, Dreesen, JD, Nilweski E, Jastrow H, Giebel B, Ergun S, Singer BB. Tumor and Endothelial Cell-Derived Microvesicles Carry Distinct CEACAMs and Influence T-Cell Behavior. PLOS One. 2013; 8(9): e74654 3.7
   
3. Görgens A, Radtke S, Moellmann M, Cross M, Duerig J, Horn PA, Giebel B. Revision of the Human Hematopoietic Tree: Granulocyte Subtypes Derive from Distinct Hematopoietic Lineages. Cell Reports. 2013; 3(5): 1539-52 8.4
   
4. Krawczyk A, Arndt MAE, Grosse-Hovestc L, Weichert W, Giebel B, Dittmer U, Hengel H, Jäger D, Schneweis KE, Eis-Hübingerg AM, Roggendorf M, Krauss J. Overcoming drug-resistant herpes simplex virus (HSV) infection by a humanized antibody. Proc Natl Acad Sci USA. 2013; 110(17): 6760-5 9.7
   
5. Schilling B, Sucker A, Griewank K, Zhao F, Weide B, Görgens A, Giebel B, Schadendorf D, Paschen A. Vemurafenib reverses immunosuppression by myeloid derived suppressor cells. Int J Cancer. 2013; 133(7): 1653-63 5.4

Publications


2013

Görgens A, Radtke S, Möllmann M, Cross M, Dürig J, Horn PA, Giebel B (2013)
Revision of the human hematopoietic tree: granulocyte subtypes derive from distinct hematopoietic lineages
Cell Rep

 

Krawczyk A, Arndt MA, Grosse-Hovest L, Weichert W, Giebel B, Dittmer U, Hengel H, Jäger D, Schneweis KE, Eis-Hübinger AM, Roggendorf M, Krauss J (2013)
Overcoming drug-resistant herpes simplex virus (HSV) infection by a humanized antibody
Proc Natl Acad Sci U S A

 

Schilling B, Sucker A, Griewank K, Zhao F, Weide B, Görgens A, Giebel B, Schadendorf D, Paschen A (2013)
Vemurafenib reverses immunosuppression by myeloid derived suppressor cells
Int J Cancer

 

Denecke B, Horsch LD, Radtke S, Fischer JC, Horn PA, Giebel B (2013)
Human endothelial colony-forming cells expanded with an improved protocol are a useful endothelial cell source for scaffold-based tissue engineering
J Tissue Eng Regen Med

 

 

2012

Gortner L, Felderhoff-Müser U, Monz D, Bieback K, Klüter H, Jellema R, Kramer BW, Keller M, Reiss I, Horn PA, Giebel B (2012)
Regenerative therapies in neonatology: clinical perspectives
Klin Pediatr

 

 Doeppner TR, Ewert TAS, Tönges L, Herz J, Zechariah A, ElAli S, Ludwig A-K, Giebel B, Nagel F, GPH, Weise J, Hermann DM, Bähr M (2012)  Transduction of Neural Precursor Cells with TAT-Hsp70 Chaperone: Therapeutic Potential Against Ischemic Stroke After Intrastriatal and Systemic Transplantation
Stem Cells

 

 Goergens, A., Beckmann, J., Ludwig, A.-K., Möllmann, M., Dürig, J., Horn, P. A., Rajendran, L., & Giebel, B. (2012)  Lipid raft redistribution and morphological cell polarization are separable processes providing a basis for hematopoietic stem and progenitor cell migration
International Journal of Biochemistry and Cell Biology (2012), doi:10.1016/j.biocel.2012.03.020 

 

 Giebel B, Wodarz A (2012)  Notch signaling: numb makes the difference
Curr Biol. 2012 Feb 21;22(4):R133-5 

 

 

2011

 Ludwig AK, Giebel B (2011)  Exosomes: small vesicles participating in intercellular communication
Int J Biochem Cell Biol. 2012 Jan;44(1):11-5 

 

 Radtke S, Horn PA (2011)  Cells, niche, fate: meeting report on the 6th International Meeting of the Stem Cell Network North Rhine Westphalia
Cell Reprogram. 2011 Oct;13(5):381-4 

 

 Sokolova V, Ludwig AK, Hornung S, Rotan O, Horn PA, Epple M, Giebel B (2011)  Characterisation of exosomes derived from human cells by nanoparticle tracking analysis and scanning electron microscopy Colloids Surf B Biointerfaces. 2011 Oct 1;87(1):146-50 

 

 2010

  Hemeda H, Jakob M, Ludwig A, Giebel B, Lang S, Brandau S.  (2010)
  Interferon-gamma and Tumor Necrosis Factor-alpha Differentially Affect Cytokine Expression and Migration Properties of Mesenchymal Stem Cells
  Stem Cells Dev. 2010 May;19(5):693-706
 

 
[Summary]   

     2009

  Rajendran L, Beckmann J, Magenau A, Boneberg EM, Gaus K, Viola A, Giebel B, Illges H.  (2009)
  Flotillins are involved in the polarization of primitive and mature hematopoietic cells
  PLoS One e8290:

 
[Summary]   

 

   2008

  Beier D, Röhrl S, Pillai DR, Schwarz S, Kunz-Schughart LA, Leukel P, Proescholdt M, Brawanski A, Bogdahn U, Trampe-Kieslich A, Giebel B, Wischhusen J, Reifenberger G, Hau P  (2008)
  Temozolomide preferentially depletes cancer stem cells in glioblastoma
  Cancer Res. 68(14): 5706-15
 

 
[Summary]   

    Giebel B, Punzel M  (2008)
  Lineage development of hematopoietic stem and progenitor cells.
  Biol Chem 389(7): 813-24
 

 
[Summary]   

    Giebel B, Bruns I.  (2008)
  Self-renewal versus differentiation in hematopoietic stem and progenitor cells: a focus on asymmetric cell divisions.
  Curr Stem Cell Res Ther 3(1): 9-16
 

 
[Summary]   

    Giebel B  (2008)
  Cell polarity and asymmetric cell division within human hematopoietic stem and progenitor cells.
  Cells Tissues Organs 188(1-2): 116-26

 
[Summary]   

 

     2007

    Giebel B, Beckmann J.  (2007)
  Asymmetric cell divisions of human hematopoietic stem and progenitor cells meet endosomes.
  Cell Cycle 6(18): 2201-4
 

 
[Summary]   

  Feldhahn N, Henke N, Melchior K, Duy C, Soh BN, Klein F, von Levetzow G, Giebel B, Li A, Hofmann WK, Jumaa H, Müschen M.  (2007)
  Activation-induced cytidine deaminase acts as a mutator in BCR-ABL1-transformed acute lymphoblastic leukemia cells.
  J Exp Med 204(5): 1157-66
 

 
[Summary]   

  Beckmann J, Scheitza S, Wernet P, Fischer JC, Giebel B. (2007)
  Asymmetric cell division within the human hematopoietic stem and progenitor cell compartment: identification of asymmetrically segregating proteins.
  Blood 109(12): 5494-501

 
[Summary]   

 

     2006 

  von Levetzow G, Spanholtz J, Beckmann J, Fischer J, Kögler G, Wernet P, Punzel M, Giebel B. (2006)
  Nucleofection, an efficient nonviral method to transfer genes into human hematopoietic stem and progenitor cells.
  Stem Cells Dev 15(2): 278-85
 

 
[Summary]   

    Giebel B, Wodarz A.  (2006)
  Tumor suppressors: control of signaling by endocytosis.
  Curr Biol 16(3): R91-2
 

 
[Summary]   

  Bracker TU, Giebel B, Spanholtz J, Sorg UR, Klein-Hitpass L, Moritz T, Thomale J.  (2006)
  Stringent regulation of DNA repair during human hematopoietic differentiation: a gene expression and functional analysis.
  Stem Cells 24(3): 722-30

 
[Summary]   

 

     2004

    Giebel B, Corbeil D, Beckmann J, Höhn J, Freund D, Giesen K, Fischer J, Kögler G, Wernet P.  (2004)
  Segregation of lipid raft markers including CD133 in polarized human hematopoietic stem and progenitor cells.
104(8 Blood 104(8: 2332-8
 

 
[Summary]   

  Schneider EM, Torlakovic E, Stühler A, Diehl V, Tesch H, Giebel B.  (2004)
  The early transcription factor GATA-2 is expressed in classical Hodgkin\\\'s lymphoma.
  J Pathol 204(5): 538-45
 

 
[Summary]